diff --git a/compiler/src/dotty/tools/dotc/ast/tpd.scala b/compiler/src/dotty/tools/dotc/ast/tpd.scala
index c04995df70a9..21ce73ee9a97 100644
--- a/compiler/src/dotty/tools/dotc/ast/tpd.scala
+++ b/compiler/src/dotty/tools/dotc/ast/tpd.scala
@@ -42,7 +42,7 @@ object tpd extends Trees.Instance[Type] with TypedTreeInfo {
     Super(qual, if (mixName.isEmpty) untpd.EmptyTypeIdent else untpd.Ident(mixName), inConstrCall, mixinClass)
 
   def Apply(fn: Tree, args: List[Tree])(implicit ctx: Context): Apply = {
-    assert(fn.isInstanceOf[RefTree] || fn.isInstanceOf[GenericApply[_]])
+    assert(fn.isInstanceOf[RefTree] || fn.isInstanceOf[GenericApply[_]] || fn.isInstanceOf[Inlined])
     ta.assignType(untpd.Apply(fn, args), fn, args)
   }