diff --git a/docs/changelog.rst b/docs/changelog.rst
index 9dd4dcf2..db3bc343 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -28,6 +28,7 @@ Changes
 - ``NapariMPLWidget.update_layers()`` has been removed as it is intended to be
   private API. Use ``NapariMPLWidget.on_update_layers`` instead to implement
   funcitonality when layer selection is changed.
+- The slice widget now only plots x-ticks at integer locations.
 
 Bug fixes
 ~~~~~~~~~
diff --git a/src/napari_matplotlib/slice.py b/src/napari_matplotlib/slice.py
index 8cbef453..e3aa80b2 100644
--- a/src/napari_matplotlib/slice.py
+++ b/src/napari_matplotlib/slice.py
@@ -1,5 +1,6 @@
 from typing import Any, Dict, Optional, Tuple
 
+import matplotlib.ticker as mticker
 import napari
 import numpy as np
 import numpy.typing as npt
@@ -116,3 +117,7 @@ def draw(self) -> None:
         self.axes.plot(x, y)
         self.axes.set_xlabel(self.current_dim)
         self.axes.set_title(self._layer.name)
+        # Make sure all ticks lie on integer values
+        self.axes.xaxis.set_major_locator(
+            mticker.MaxNLocator(steps=[1, 2, 5, 10], integer=True)
+        )
diff --git a/src/napari_matplotlib/tests/baseline/test_slice_2D.png b/src/napari_matplotlib/tests/baseline/test_slice_2D.png
index c9e4d6f6..5b73091c 100644
Binary files a/src/napari_matplotlib/tests/baseline/test_slice_2D.png and b/src/napari_matplotlib/tests/baseline/test_slice_2D.png differ