diff --git a/packages/node/src/sdk/initOtel.ts b/packages/node/src/sdk/initOtel.ts
index 27423a3d033a..5cd50e2711c1 100644
--- a/packages/node/src/sdk/initOtel.ts
+++ b/packages/node/src/sdk/initOtel.ts
@@ -1,5 +1,5 @@
 import moduleModule from 'module';
-import { DiagLogLevel, diag } from '@opentelemetry/api';
+import { DiagLogLevel, context, diag, propagation, trace } from '@opentelemetry/api';
 import { Resource } from '@opentelemetry/resources';
 import type { SpanProcessor } from '@opentelemetry/sdk-trace-base';
 import { BasicTracerProvider } from '@opentelemetry/sdk-trace-base';
@@ -127,11 +127,10 @@ export function setupOtel(client: NodeClient, options: AdditionalOpenTelemetryOp
     ],
   });
 
-  // Initialize the provider
-  provider.register({
-    propagator: new SentryPropagator(),
-    contextManager: new SentryContextManager(),
-  });
+  // Register as globals
+  trace.setGlobalTracerProvider(provider);
+  propagation.setGlobalPropagator(new SentryPropagator());
+  context.setGlobalContextManager(new SentryContextManager());
 
   return provider;
 }
diff --git a/packages/opentelemetry/README.md b/packages/opentelemetry/README.md
index bc4266c85ce0..86a644f5c467 100644
--- a/packages/opentelemetry/README.md
+++ b/packages/opentelemetry/README.md
@@ -60,6 +60,7 @@ import {
   setOpenTelemetryContextAsyncContextStrategy,
 } from '@sentry/opentelemetry';
 import { AsyncLocalStorageContextManager } from '@opentelemetry/context-async-hooks';
+import { context, propagation, trace } from '@opentelemetry/api';
 
 function setupSentry() {
   Sentry.init({
@@ -77,10 +78,9 @@ function setupSentry() {
   const SentryContextManager = wrapContextManagerClass(AsyncLocalStorageContextManager);
 
   // Initialize the provider
-  provider.register({
-    propagator: new SentryPropagator(),
-    contextManager: new SentryContextManager(),
-  });
+  trace.setGlobalTracerProvider(provider);
+  propagation.setGlobalPropagator(new SentryPropagator());
+  context.setGlobalContextManager(new SentryContextManager());
 
   setOpenTelemetryContextAsyncContextStrategy();
 }
diff --git a/packages/opentelemetry/test/helpers/initOtel.ts b/packages/opentelemetry/test/helpers/initOtel.ts
index 18e7f1e3d867..121ca0181892 100644
--- a/packages/opentelemetry/test/helpers/initOtel.ts
+++ b/packages/opentelemetry/test/helpers/initOtel.ts
@@ -1,4 +1,4 @@
-import { DiagLogLevel, diag } from '@opentelemetry/api';
+import { DiagLogLevel, context, diag, propagation, trace } from '@opentelemetry/api';
 import { AsyncLocalStorageContextManager } from '@opentelemetry/context-async-hooks';
 import { Resource } from '@opentelemetry/resources';
 import { BasicTracerProvider } from '@opentelemetry/sdk-trace-base';
@@ -69,11 +69,9 @@ export function setupOtel(client: TestClientInterface): BasicTracerProvider {
   // We use a custom context manager to keep context in sync with sentry scope
   const SentryContextManager = wrapContextManagerClass(AsyncLocalStorageContextManager);
 
-  // Initialize the provider
-  provider.register({
-    propagator: new SentryPropagator(),
-    contextManager: new SentryContextManager(),
-  });
+  trace.setGlobalTracerProvider(provider);
+  propagation.setGlobalPropagator(new SentryPropagator());
+  context.setGlobalContextManager(new SentryContextManager());
 
   return provider;
 }
diff --git a/packages/vercel-edge/src/sdk.ts b/packages/vercel-edge/src/sdk.ts
index efb3a8dfcd0c..8c3939d26cba 100644
--- a/packages/vercel-edge/src/sdk.ts
+++ b/packages/vercel-edge/src/sdk.ts
@@ -1,4 +1,4 @@
-import { DiagLogLevel, diag } from '@opentelemetry/api';
+import { DiagLogLevel, context, diag, propagation, trace } from '@opentelemetry/api';
 import { Resource } from '@opentelemetry/resources';
 import { BasicTracerProvider } from '@opentelemetry/sdk-trace-base';
 import {
@@ -171,11 +171,9 @@ export function setupOtel(client: VercelEdgeClient): void {
 
   const SentryContextManager = wrapContextManagerClass(AsyncLocalStorageContextManager);
 
-  // Initialize the provider
-  provider.register({
-    propagator: new SentryPropagator(),
-    contextManager: new SentryContextManager(),
-  });
+  trace.setGlobalTracerProvider(provider);
+  propagation.setGlobalPropagator(new SentryPropagator());
+  context.setGlobalContextManager(new SentryContextManager());
 
   client.traceProvider = provider;
 }